Nonsolvent Water in Human Erythrocytes and Hemoglobin Solutions
نویسنده
چکیده
Distribution ratios of water-soluble nonelectrolytes have been measured for two systems, human red bood cells/isotonic saline and hemoglobin solutions/water. The results show that for these solutes there is a significant amount of nonsolvent water associated with Hb. However, the amount of this nonsolvent water depends markedly on the temperature, as well as on the size, steric configuration, and functional groups of the probe solutes. The significance of the data is discussed.
منابع مشابه
Nonsolvent Water in Human Erythrocytes
From the ability of a concentrated suspension of human erythrocytes to regulate the pH of unbuffered, anisotonic, external media it is possible to calculate the fractional cell volume in which chloride is dissolved. The difference between this volume and the total cell water gives the nonsolvent water (for chloride) of the cell. Nonsolvent water is less than 3 % of the isotonic cell volume. The...
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عنوان ژورنال:
- The Journal of General Physiology
دوره 50 شماره
صفحات -
تاریخ انتشار 1967